Imunology

Antigen Specific IgG4 in Patients with Gastrointestinal Complaints

Viktorija Priedite, Jevgenij Nikiforenko, Natalja Kurjane and Juta Kroica
Laboratory Management and Consultancy, Riga, Latvia.
Department of Biology and Microbiology, Riga Stradins University, Riga, Latvia.

Aims: To find the antigen specific IgG4 in patients with gastrointestinal complaints and in control group, to demonstrate suitability of detection of IgG4 by using antigen panel.
Place and Duration of Study: Laboratory Management and Consultancy, Riga, Latvia, October 2012 – February 2013.
Methodology: The study included 147 patients (46 men, 101 women, aged from 1 to 76) with different complaints regarding gastrointestinal habitus. Antigen specific IgG4 analysis by using regional adopted antigen panel was executed.
Results: Almost all patients with gastrointestinal complaints -141 out of 147-have at least 2nd level antibodies, while in control group 15 out of 24 have 2nd level of antibodies.
Conclusion: IgG4 antigen specific antibody tests by panels could be used as a screening tool for food intolerance detection.

Keywords :
Antigen specific IgG4; food intolerance.

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